India’s Tuberculosis fight may get a shot in the arm | India News – Times of India

PUNE: In an effort to stop the transmission of tuberculosis, the Indian Council of Medical Research (ICMR) is at an advanced stage of developing a tuberculosis vaccine.
“Currently, the ICMR’s Indian Tuberculosis Research Consortium is conducting a multicenter study to study the efficacy and safety of two candidate vaccines against tuberculosis,” said Dr. Suchit Kamble, senior researcher at the ICMR National AIDS Research Institute (NARI).
The phase 3 trials, which are expected to be over by 2024, after which patient data will be compiled and results will be analyzed, Kamble said.
The Phasebo-controlled Phase 3 studies are currently being conducted at 18 sites in six states – Maharashtra, Tamil Nadu, Hyderabad, Delhi, Telangana and Odisha. The trial includes subjects over six years of age.
Childhood TB is still a major problem and contributes to about 31% of the global burden.
ICMR’s National AIDS Research Institute (NARI) is also involved in the study and conducts trials in two of its clinics. Tuberculosis is very common among HIV-positive people with low immunity.
Researchers are hopeful about positive results from the study that have the potential to help the country stop the spread of tuberculosis in the future.
India experienced a sharp increase of 19% in tuberculosis cases in 2021 compared to the previous year, even when a large majority of 64% of the surveyed symptomatic population did not seek medical care between 2019 and 2021, the recently released India TB Report 2022 and National TB Prevalence Survey shows.
A total of 19.33 lakh new and recurrent tuberculosis patients were reported in 2021, compared with 16.28 lakh the previous year. Deaths due to tuberculosis also increased to 4.93 lakh, excluding HIV patients, in 2020, an increase of 13% from a year ago, while mortality due to all forms of tuberculosis between 2019 and 2020 increased by 11%.
Delhi, with 534 cases per 1 lakh population, has the highest prevalence of TB, followed by 484 in Rajasthan, 481 in Uttar Pradesh and 465 in Haryana and 454 in Chhattisgarh. Kerala has the lowest prevalence at 115 per 1 lakh people.

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